Browsing by Subject "spinal cord injury"
Now showing items 1-15 of 15
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(2018-01-23)Over 90% of spinal cord injuries are caused by traumatic accidents and are often associated with secondary tissue damage that can provide a source of continued pain input. Previous work has shown that nociceptive stimulation ...
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(2011-05-05)Spinal cord injury (SCI) currently affects over 250,000 people in the United States alone with approximately 11,000 new cases occurring each year. In addition to its debilitating physical consequences, spinal cord injury ...
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(2013-07-16)Approximately two-thirds of patients will experience pain following spinal cord injury (SCI). This pain can arise as an immediate consequence of SCI, or can develop over time into chronic, neuropathic pain. Individuals ...
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(2020-04-20)Hb9 (Mnx1) is a transcription factor described as a spinal cord motor neuron-specific marker in embryonic development and a critical factor for the post-mitotic specification of these cells. As such, transgenic mice with ...
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(2022-07-27)Spinal cord injury (SCI) is a traumatic event that can result in loss of motor, sensory, and autonomic functions. There is currently no cure for SCI, but potential treatments and therapies are informed by knowledge of how ...
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(2017-05-02)Opioids are amongst the most effective and widely prescribed medications for the treatment of pain following spinal cord injury (SCI). Spinally-injured patients receive opioids shortly upon arrival at the emergency room, ...
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(2022-05-18)Opioids are among the most effective analgesics for the management of pain in the acute phase of a spinal cord injury (SCI), and approximately 80% of patients are treated with morphine in the first 24 hours following SCI. ...
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(2016-06-09)The purpose of the present study was to examine the role of depression and anxiety in predicting time to pressure ulcer occurrence and time to severe pressure ulcer occurrence during inpatient spinal cord injury (SCI) ...
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(2014-08-26)Spinal cord injury (SCI) leads to increased anxiety and depression in as many as 60% of patients. Yet despite extensive clinical research focused on understanding the variables influencing psychological well-being following ...
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(2012-10-19)This study aimed to model the trajectories of life satisfaction as influenced by functional impairment and family satisfaction over a five-year period following spinal cord injury, severe burns, and lower-extremity fractures. ...
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(2009-05-15)Research has shown that exposure to just 6 minutes of uncontrollable shock 24 hours following contusion injury impairs locomotor recovery and leads to greater tissue loss at the injury epicenter. Uncontrollable shock is ...
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(2017-08-02)Small-animal models such as rodents and non-human primates play an important pre-clinical role in the study of human disease, with particular application to cancer, cardiovascular, and neuroscience models. To study these ...
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Spinal cord injury (SCI) is a devastating event that typically results in immediate and permanent loss of neurological due to massive disruption of neuronal circuits. This can lead to many complications including, but not ...
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(2021-09-29)Pain input after spinal cord injury can be detrimental to acute and long-term processes. In a rodent model of incomplete spinal cord injury, it has been shown that nociceptive stimulation (pain input) administered below ...
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(2015-11-11)Traumatic spinal cord injuries are often accompanied by secondary injuries that complicate the recovery process. Our lab has shown that nociceptive stimulation engages pain fibers and negatively impacts recovery following ...